芬奇的世界Finch's WorldScience, memory, and the unseen

Science News — 論文導讀（2D 圖解 + 3D 動畫）

1. 3D 粒線體斑塊：阿茲海默症中的清除失靈Why do damaged mitochondria accumulate in Alzheimer’s disease? Nature Neuroscience 2026 · DOI 10.1038/s41593-026-02390-1 · 2D + 3D
2. 3D 老化與代謝對大腦健康的影響是分開的兩條軸線Aging and metabolism contribute separately to brain-body health PLOS Biology 2026 · DOI 10.1371/journal.pbio.3003856 · 2D + 3D
3. 3D 粒線體 Complex I 與 ROS 透過相反機制控制神經肌肉功能Mitochondrial Complex I and ROS control neuromuscular function through opposing pre- and postsynaptic mechanisms PLOS Biology 2025 · DOI 10.1371/journal.pbio.3003388 · 2D + 3D
4. 3D 老化細胞建構大腦屏障Persistent and transient senescent cells contribute to brain-barrier development Cell 2026 · DOI 10.1016/j.cell.2026.05.022 · 2D + 3D
5. 3D 血液基因表達預測 ALS 疾病狀態與存活Gene expression signatures from whole blood predict amyotrophic lateral sclerosis case status and survival Nature Communications 2025 · DOI 10.1038/s41467-025-64622-5 · 2D + 3D
6. 3D Caspase-4 驅動 TDP-43 細胞質病理Caspase-4, TDP-43 and ALS Nature Communications 2026 · DOI 10.1038/s41467-026-73724-7 · 2D + 3D
7. 3D Alpha-synuclein 類澱粉蛋白作為酵素破壞 ATPα-Synuclein amyloids degrade ATP Scientific Reports 2025 · DOI 10.1038/s41598-025-32888-w · 2D + 3D
8. 3D 人類蛋白質體的擴張：微蛋白與 peptideinMicroproteins and peptideins Nature 2026 · DOI 10.1038/s41586-026-10459-x · 2D + 3D
9. 3D 腸道微生物與大腦健康的雙向對話Bidirectional crosstalk between the gut microbiota and cellular compartments of brain: Implications for neurodevelopmental and neuropsychiatric disorders Translational Psychiatry 2025 · DOI 10.1038/s41398-025-03504-2 · 2D + 3D